Rossington Main will start as slight underdogs when they welcome West Didsbury & Chorlton to Oxford Street in the FA Vase on Saturday (3pm).
The visitors ply their trade in the North West Counties Premier - a tier higher than Rossington.
However, the Lancashire outfit are in the bottom half of the table with just three wins from nine league outings, which should give Steve Lodge’s troops some encouragement that they can cause an upset.
Meanwhile, Rossington slumped to their heaviest defeat of the season last weekend losing 6-1 at Pontefract Collieries.
Liam Radford, Nick Handley and Andre Catton fired Collieries into a 3-0 lead inside the opening 35 minutes.
Catton grabbed his second and Pontefract’s fourth just four minutes into the second half to put the game out of Rossington’s reach.
Jonathan Cook pulled one back on 66 minutes from the penalty spot following a handball.
But the home side ran in two more through Radford and a Kingsley Wetherald chip.
It has been an eventful week for Maltby Main. Brian Cusworth stepped down as manager after just nine games in charge but will remain at the club as a player.
The Miners moved quickly to appoint former Doncaster Rovers and Preston North End striker Mick Norbury as their new boss. Norbury watched from the stands as Maltby lost 3-1 at Staveley Miners Welfare in midweek before taking up his managerial duties in the dugout last weekend.
His tenure got off to a winning start with a 3-1 victory at Lincoln Moorlands Railway.
Goals from Sam Forster and a Cusworth double earned the Miners their first win since the opening day of the season.