More than 39,000 smokers in Yorkshire and the Humber region kicked the habit between April 2010 and April 2011 with help from the NHS.
Figures issued by the NHS Information Centre also show that more than 73,000 people made a commitment to stub out their cigarettes for good by setting a date to quit.
For information about your local NHS stop smoking services visit www.nhs.uk/smokefree or call 0800 022 4 332.
Regional director for public health at NHS Yorkshire and the Humber, Paul Johnstone, said:
“This is great news, the more people that give up smoking the better.
“The NHS stop smoking services in the region continue to do a fantastic job helping to make people aware of the risks of smoking and offering lots of practical advice on how to give up.
“Parents who quit smoking will also be improving the health of their children by ensuring they do not expose them to harmful second hand smoke.”
By reducing the number of smokers in Yorkshire and Humber region, the NHS can also cut down on the many thousands of smoking related procedures and operations it carries out every year, saving the NHS time and freeing up funds which can be spent elsewhere.